Protein Evolution

The Probability of Insulin Evolving

The calculation for the amount of information in the insulin A and B chain is based strictly on mathematics. No interpretation is required. The same cannot be said for molecular knowledge. Molecular knowledge requires finding the minimum information that preserves some functionality.

   It is a mistake to calculate the odds for the evolution of insulin based on the information in insulin. It is extremely important to use the minimum information that results in a protein with some selective advantage. In other words, molecular knowledge must be used to calculate the probability associated with a protein evolving, and molecular knowledge can only be found by using math along with human insight.

   In this chapter, the information in insulin is found to be 189 bits, and the molecular knowledge is calculated at 127 bits. Figure 4.7 illustrates the steps that chance must overcome.

Figure 4.7: Molecular Knowledge in Insulin



                 

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